The study, titled, “ Genetic variation of putative myokine signaling is dominated by biologic sex and sex hormones,” published in eLife, is the first to evaluate how genetic architecture influences muscle signaling to other tissues, highlighting that sex and estrogens are critical determinants of these processes. This new discovery provides insight into how muscle functions, such as exercise, promote healthy longevity, metabolism and improve cognition. Newswise - Irvine, CA – – A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females. News Research News Releases Journal News Medical News Science News Life News Business News Expert Pitch Google Fact Check Research Alert Marketplace News With Video/Audio Multimedia RSS Feeds by Latest News Coronavirus News Currently Embargoed